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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f7c85e6bc2c1ef5db01d5753cd7a0bc3f19cb2f1151d58699900d76a2f51f7b' 
  AND token = '74XDf/GRJGSizSldKbOffEV5EEttGAsFZSIplWNuMyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}