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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e0eebd5aee9ca3f49faa1ddfaa1eb4c065bc3a30b0c8491d5d5d05bb9db3366' 
  AND token = 'TQin5dGsmFApng4rS1CZpuma9w1lDRMAq+tkMZ4S1+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}