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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa261291155cb6a61e41463b55f8ddcb763c0d6679ca5a93cce6757f709b5411' 
  AND token = 'Tb3FOreYE8tNewCEU22zz4IMxCOgrnunpd+1mF3U/mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}