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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '952f8ef60a1753198261d3634eebbd4ece3cb2544f2bc68c69de84b95739b3c6' 
  AND token = 'KwS+aURpwSqiwT63tonAtkk/vQiG0UTqi5/xMjyaMu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}