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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5258c813a33689d04ab3fa1eca52b29a5a31dd8e84b978427798137496672515' 
  AND token = 'F8m9uE8oOihgh9sJAcY4lnUfdqPYvYunQhlKhEw0kuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}