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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ea297ab0d4db49f453b6ef373949ca5adf73a6eae32772072f54e2be7427b0' 
  AND token = 'vR+T/es8OIGvQBIeHQdDR8q5XOQwjWIkbLGiq5x0hvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}