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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168176eec7fee7f1897adc1bbbeff8a39a8250b2ee37c4594e077258c3f67a95' 
  AND token = 'YLXp3BQLq1isijBsqwo2OsQf1WWdm5D9wwMgETrQu54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}