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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9571e6e7dab3195055bb527d45fcba536ae57c0df26fa04b0c28181c3bfeca' 
  AND token = '+OxpwTQFjLNxrHHr8J0omDGQCGmyOb8oTcyDwaK/i7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}