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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27dd4a770c19394c444e889e8b01feb81aebc8dfe305e8077905ef83801cf12f' 
  AND token = 'MBkSI7ggKDxnwPOyiiyQg3vp9uxFuN8Z8I2zatNpARA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}