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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d649ded1bf4722bc0392ea258d30caeab4ad530bcf028825d12e7b08fb99e9' 
  AND token = 'UZw9kaP4nu25rZRmOgEG6P7SyJ4KmVwoq3H78Q7ThQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}