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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849b6b4e996d758a6af84a9dbe68a95ea08ae2b020279736cde09df2015e9bb4' 
  AND token = 'WUqSoyKrR0wEoZH3wl0+YPcknKI1DdMo5VRXe/DWkxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}