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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f8da8231d325e021be93fd536b718bcc472aef3061090124e3841a027d8c22' 
  AND token = '1J0s3Q9gokxRMKNHA+M2UROaq3DO0CsdGdqkBmXTz1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}