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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b20880a98cfec7761ef06222c312b0e81f80999a486b6f2be0061c9a006e3f74' 
  AND token = '4qwku8LYBOC2vkdgBOMZoaBRgnKEq0FMgZs7nwBy8a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}