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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea2f73453d9a73ca287f0e240aec909f5fea55652c2b454111df507a1b9899a' 
  AND token = 'cspFPeVHicoLst2uQyfU+uZpdGKozkH0wiUvtFN1UQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}