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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451d90a4249953d7c85e70b968d1ecd0dfbfda9969a9da58e2aea8456a1a96ce' 
  AND token = '2npZdyz6DeO4ZYR3wuGdldRzy/8HMtfLOA6yTz/BLtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}