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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3679035167743a160c05d07d6ff98e874819e8c9a0e5fdbe0eae5f3eade69b' 
  AND token = '8FaeiOBvth+JH+YRbKFV4ZDrAgdpnKJdv6WUbW8+Pxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}