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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '099034be240d837ac422b13beaa7de68fb34e3f2bf79b5866e08dc2b4c342833' 
  AND token = 'ph51z3pOJS6U2hnRvrb3LkchV32vmvTTtdwVeRTGKgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}