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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4ac895c84c4a7ce0d262d5066e5418d977111123e60cf052023fad78689f4e' 
  AND token = 'aVGedIcT9zhevm2E5HXmaf+U157I0pKKuSMEXE2psFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}