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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800161d89886757f43c10efd581f56286bb1f0c7bf494fd8c22594b071b282e2' 
  AND token = 'cCQaQuAIV/B03InZS9Mx68/iwEKFETHaIfZLSN4LuDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}