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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8f5de6b455de1d21e9c4b334d42f864b8602304f064ab6f056aaf871c90208' 
  AND token = 'HUgUTzWeHOFhvPpvt/eXrD4I2MX3nMGMuEr4wulbNOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}