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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863a2bd51eb76e2e8e0dcaece15e1d18ab2e5692cd13a64a89c541327925d778' 
  AND token = 'qs10qUYnQ5UzyzSQXdlPvx7CEpzyarV+Gu8sGcApZwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}