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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24498c094fe2c06cdbe5a208f0450bdff82a96983c321883e20e00d0617e3a13' 
  AND token = 'seJhr0d69d5Otc/RWKkvAt9YX8NtA7V62DV/LrIcOrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}