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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cfbf18dbc31be7388f1da0cc927705ce2f7f1369307b2c75780a8d287f8bbe4' 
  AND token = '6eRoAmHc9EQR76mwo0cE8HyIdVeqC4hoimy0RStTNyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}