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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14218ed3ba655eab02b75f3fa4d9a2bc21730b21588eb9962a520e5248bfcfe8' 
  AND token = 'q7PbAFThzJnPZvWv/oJWI524id+DYCMCy1zBOoklyR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}