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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d1b9fc328f42007b4338b829037b9a161693ebaa9ac53d9a03c0f379308502e' 
  AND token = 'yZgC/pTcTaMwGBunlgiwpmn7kceyvStm9ggGikUJWOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}