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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db501a22d37993ce75d2a8423ebca492e5a44e2e1bf83531072a7b3111121b29' 
  AND token = 'EXHzcR2JyN+nwusZL12SH2nvVNMnrb23d1iIfHuaWd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}