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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1024eeaaceb090bbc54a7bc2a76746d3ca3ed85da648a6422f636b8957d9661' 
  AND token = '+q/AT362x2FjWtHQlHQV7poNNiOFKHCvBGeg/xnOofI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}