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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8126b4234bc9bca9c3d463175943e364db5c12ae17bed37e3f29a3875b9d6e72' 
  AND token = 'JN8MGAvpWD9akj+rfa9L5hUE1gilWWfLcrOs1UtMAB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}