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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53a33e71b9d7ca0e067e294d29ce9ba4994928660ce2546b5f2185c05967046' 
  AND token = 'X3bpcA0Hzqfn5AYaXAGKMGW6MxPsHnpFGb7KJo8G4cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}