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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f169a480ff319993161e14028d57ff004b5c970e3b7f24ca60941407776e75' 
  AND token = 'LuIrp3T0ZJirdDtNqGCtJSUV5LojVLVETxBnfRBM2hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}