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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4846c20dacb8e0eed8acd19f26431bb7a2481fd914f380c6bc1f084b1547397' 
  AND token = 'bV1qM9SgEOicW1pUG7X5xWbxYHg33CMfz8zIrOB6ppg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}