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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0e49fc4bc365b04d29fb4cc0dd5d63c055ec1c8328761bbbfb0291f2b1f4a8' 
  AND token = 'BNPM6LWWYp3ck8GRYimEbvDgqWZfteq6a9bU/9UUg7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}