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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee9b845951b34e1ae980d96b50f86fdd81a9ba0575a9ce5b04e56251a853d967' 
  AND token = 'Jk6GqOYUswuHDlrV6dFqH4coNUtYv8FaTXFVR5ZVWqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}