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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287a8d7038b4ba4e6ecb13dbbc1827eba7d8246358b32d2e1d4a13171344d8b1' 
  AND token = 'AutB11EkBGG2hG9K0HKuuob+xEa+9XMjqOZZnGU3SyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}