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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5163701c993dd4c2306e8fb4e9af00409e741d00dd239c28fbe303c8f073d302' 
  AND token = 'yqyivk/ceIqij0SaXRl0wh7V3nL+AxQNmgm2ryk2GEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}