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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8537f9d364da1ac09192b1f1c250baf1d2b731fbda036f1f116655db94ef6a' 
  AND token = 'BzfDZKkI8K29+te3Z953O+cYbpwHR7JHtWlUw3UZMQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}