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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a61fd4a53ae2998b43385876e07317306bcd2ab1e5913b22ed4bfa2d8ce8545' 
  AND token = 'ThZtUV2mxZSrzM/I3u2qad0zGVosTbpbgG8i0o01SpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}