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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7a1cbc5cf89203ffe22bfed7f2fc003a04d99121c04095743f1df6e3fc6c07c' 
  AND token = 'G5Mnt69jM8xBLIlB+XXU4EowaVLSlSyfbt0UBZVDkM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}