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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0dfc44369e84ea7bf5356ba7da3111f75cdb9b3ee2197f853f1a85a478e4c1a' 
  AND token = 'IjctnEO9Kpr4/9LSuhOchqLpOppCL5rmITS0pmPg8/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}