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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6971f59e4c0a0956bdefa299f7687d9b73bff88ffa8fa81fe08c7dc294b45d' 
  AND token = 'k9TxdxSrcFKGp3C6P9+JHwBGsuLJP/QAned0q7rhUAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}