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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a50987bb8e083ad3f6f08f3b489de6327da8f0270e102a02e6284660683e160' 
  AND token = 'C6ZXuziBJiNkYbjGEXMhTXWvTzxsp74xWoqjdqNPiAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}