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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66c9e4ba8341d1cbe098238b7200a490dd91984374afacc76068b2c00286f66' 
  AND token = 'ieNbjggAy6rUg4NOxGJ/4HPZ1phCftG45fJpVqgSlHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}