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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a465a7a731c94fa2fffd384e30aec9a6acd2c43c3dca2c0b36edef3cf6b7c14' 
  AND token = 'oqsa2iIDvnYs9IQl/8HOK7RtWAI2bUh9XnaZtR4vnWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}