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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd298f22a43c20d25f111fbee8eaf6a32291fa2eb187719ceb914f4b51e3d2703' 
  AND token = 'zuWmnR1R4fA8Wk7pwhVQbpWcWWcxJ+0lHRb13sQZ/YU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}