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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1009b01e6741cd541c6d7a163351bd1d72679e39c995deae57f38532252a21bc' 
  AND token = '4Ke1Y6a5H/oVdrM0kLCNLBRVGFlefr8i5HMkbd8Qnoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}