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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e09d48ea4160c722e9c111b5a307f7fd6c589c8cee4360b79d30d9364b4e4a1' 
  AND token = 'qw13RiubRlSMxlZ2bokbskuydOKmIDv8noLM/FOx5LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}