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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3ace700ef8bd1a28501eea543fec5497ad466d80fac7877d9e53377a99650d' 
  AND token = 'KX1SD1vrN8Cn59yCbbyueVfoc+bvLcigybA0mT2JY/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}