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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b59217d13a1e7101cbdf4b5291d8f49b3af1a55493ada3a7e58039b479fa4f' 
  AND token = 'pPyMwOiSzi2jackNKYBbc9bVxL/0hH/ZR02M8Nbta4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}