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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111b21de44c266fc0f9677d3b6aca7a84982e0829cff88fd84992b135e7c484c' 
  AND token = 'UORCUnGTpuNC0dtcioWKoK5ANH7OFf/CcS4rLwyla8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}