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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5cfa7b18d7d14addb638a63dd4b31eaa003251c9d1f4e71fc972450ed241ed' 
  AND token = 's0J43RBk2UkzszjSomrPEvsyFotW3xJSrLIsT6M++10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}